Sam Morabito

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sam.morabito{at}cnag.eu

I am a Postdoctoral Researcher in the Single Cell Genomics Group at the Centro Nacional de Análisis Genómico in Barcelona, Spain. My research focuses on applying single-cell and spatial -omics to human diseases, including neurodegeneration and cancer. I also work on bioinformatics method development, including the R package hdWGCNA. I earned my PhD in Mathematical, Computational and Systems Biology (MCSB) at the University of California Irvine in lab of Dr. Vivek Swarup.

Outside of the lab, my favorite things to do include making and drinking specialty coffee, playing with my cats Kiki and Junior, listening to music (mostly metal!), and gaming.

news

Jan 17, 2024 Today I successfully defended my PhD dissertation!
Jul 26, 2023 Our new study of spatial and single-nucleus transcriptomics in genetic and sporadic Alzheimer’s Disease is now out on bioRxiv! Check out the pre-print here.
Sep 23, 2022 hdWGCNA, an R package that I developed for performing co-expression network analysis in single-cell and spatial transcriptomics data, is now on bioRxiv! hdWGCNA uses Seurat objects and essentially begins where the Seurat tutorial ends. Check out the hdWGCNA manuscript on bioRxiv and the hdWGCNA R package on GitHub.
Aug 27, 2022 I was recently awarded a Predoctoral Individual National Research Service Award (F31) from the National Institute on Aging for my research proposal titled “Single-cell epigenomic roadmap of Alzheimer’s disease”. This preliminary results for this project can be found in my Nature Genetics paper. I am immensely thankful for the support system in my lab and at UC Irvine that helped me to achieve this fellowship.

selected publications

  1. cr_march2024.jpg
    Relapse to cocaine seeking is regulated by medial habenula NR4A2/NURR1 in mice
    Jessica E. Childs* ,  Samuel Morabito* ,  Sudeshna Das ,  Caterina Santelli ,  Victoria Pham , and 7 more authors
    Cell Reports, 2024
  2. bioRxiv
    Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer’s Disease
    Emily Miyoshi* ,  Samuel Morabito* ,  Caden M. Henningfield ,  Negin Rahimzadeh ,  Sepideh Kiani Shabestari , and 19 more authors
    bioRxiv, 2023
  3. cellrepmeth_2023.jpeg
    hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data
    Samuel Morabito ,  Fairlie Reese ,  Negin Rahimzadeh ,  Emily Miyoshi ,  and  Vivek Swarup
    Cell Reports Methods, 2023
  4. natgen_july2021.png
    Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s disease
    Samuel Morabito* ,  Emily Miyoshi* ,  Neethu Michael ,  Saba Shahin ,  Alessandra Cadete Martini , and 5 more authors
    Nature Genetics, 2021