ComputeDistance

Computes either the Euclidean or E-distance between groups in a Seurat object, depending on the chosen method.

Usage

ComputeDistance(
  seurat_object,
  groupby,
  reduction,
  method = "edist",
  verbose = TRUE
)

seurat_object: An object of class Seurat.
groupby: An object of class character. Points to the column in the Seurat object's meta data that contains the group labels.
reduction: An object of class character. The reduction / embedding in seurat_object that is used to compute the distance. Can be "pca", "harmony", or any linear dimensionality reduction.
method: An object of class character. The distance calculation method, either "euclidean" or "edist".
verbose: An object of class logical. If TRUE, prints messages. Default is TRUE.

Returns an object of class data.frame containing the distance between each pair of groups.