This function models the expression of a selected feature as a zero-inflated negative binomial (ZINB) distribution.
Usage
ModelZINB(
seurat_obj,
feature,
cells_use = NULL,
layer = "counts",
slot = "counts"
)
Arguments
- seurat_obj
A Seurat object
- feature
List of cell barcodes from the Seurat object
- slot
Slot to extract data for aggregation. Default = 'counts'
Value
The zero-inflated negative binomial model fit to the observed data from the selected feature.
Details
ModelZINB is an internal helper function that calls on zeroinfl from the pscl package to
model expression of a selected feature.