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Data setup

Functions to set up the Seurat object for network analysis

SetupForWGCNA()
SetupForWGCNA
SelectNetworkGenes()
SelectNetworkGenes
FindMajorIsoforms()
FindMajorIsoforms

Metacells and metaspots

Functions for constructing metacells from single-cell data and metaspots from ST data

MetacellsByGroups()
MetacellsByGroups
MetaspotsByGroups()
MetaspotsByGroups

Network Analysis

Functions for constructing the co-expression network

TestSoftPowers()
TestSoftPowers
TestSoftPowersConsensus()
TestSoftPowersConsensus
PlotSoftPowers()
PlotSoftPowers
ConstructNetwork()
ConstructNetwork
ModuleEigengenes()
ModuleEigengenes
ModuleConnectivity()
ModuleConnectivity

Network Visualization

Functions for visualizing the co-expression network

PlotDendrogram()
PlotDendrogram
ModuleNetworkPlot()
ModuleNetworkPlot
HubGeneNetworkPlot()
HubGeneNetworkPlot
RunModuleUMAP()
RunModuleUMAP
ModuleUMAPPlot()
ModuleUMAPPlot

Differential analysis

Functions for differential module eigengene analysis

FindDMEs()
FindDMEs
FindAllDMEs()
FindAllDMEs
PlotDMEsVolcano()
PlotDMEsVolcano
PlotDMEsLollipop()
PlotDMEsLollipop

Enrichment Analysis

Functions for Enrichr analysis and DEG overlap analysis

RunEnrichr()
RunEnrichr
EnrichrBarPlot()
EnrichrBarPlot
EnrichrDotPlot()
EnrichrDotPlot
OverlapModulesDEGs()
OverlapModulesDEGs
OverlapBarPlot()
OverlapBarPlot
OverlapDotPlot()
OverlapDotPlot

Plotting

Functions for generating plots with hdWGCNA

ModuleFeaturePlot()
ModuleFeaturePlot
ModuleRadarPlot()
ModuleRadarPlot
PlotModuleTrajectory()
PlotModuleTrajectory

Transcription Factor Regulatory Networks

MotifScan()
MotifScan
ConstructTFNetwork()
ConstructTFNetwork
AssignTFRegulons()
AssignTFRegulons
GetTFTargetGenes()
GetTFTargetGenes
TFNetworkPlot()
TFNetworkPlot
RegulonScores()
RegulonScores
RegulonBarPlot()
RegulonBarPlot
RunEnrichrRegulons()
RunEnrichrRegulons
ModuleRegulatoryNetwork()
ModuleRegulatoryNetwork
ModuleRegulatoryNetworkPlot()
ModuleRegulatoryNetworkPlot
ModuleRegulatoryHeatmap()
ModuleRegulatoryHeatmap
FindDifferentialRegulons()
FindDifferentialRegulons
PlotDifferentialRegulons()
PlotDifferentialRegulons

Module Preservation

Functions for performing module preservation analysis

ProjectModules()
ProjectModules
ModulePreservation()
ModulePreservation
ModulePreservationNetRep()
ModulePreservationNetRep
PlotModulePreservation()
PlotModulePreservation
PlotModulePreservationLollipop()
PlotModulePreservationLollipop
ModuleTopologyHeatmap()
ModuleTopologyHeatmap
ModuleTopologyBarplot()
ModuleTopologyBarplot

Module Trait Correlation

Functions for performing module trait correlation analysis

ModuleTraitCorrelation()
ModuleTraitCorrelation'
PlotModuleTraitCorrelation()
PlotModuleTraitCorrelation

Transcription Factor Networks

MotifScan()
MotifScan

Getters and setters

Functions to retrieve and set the values for various attributes

SetActiveWGCNA()
SetActiveWGCNA
GetActiveWGCNA()
GetActiveWGCNA
SetMetacellObject()
SetMetacellObject
GetMetacellObject()
GetMetacellObject
SetWGCNAGenes()
SetWGCNAGenes
GetWGCNAGenes()
GetWGCNAGenes
SetDatExpr()
SetDatExpr
GetDatExpr()
GetDatExpr
SetMultiExpr()
SetMultiExpr
GetMultiExpr()
GetMultiExpr
SetWGCNAParams()
SetWGCNAParams
GetWGCNAParams()
GetWGCNAParams
SetPowerTable()
SetPowerTable
GetPowerTable()
GetPowerTable
SetNetworkData()
SetNetworkData
GetNetworkData()
GetNetworkData
SetModules()
SetModules
GetModules()
GetModules
GetHubGenes()
GetHubGenes
SetMEs()
SetMEs
GetMEs()
GetMEs
SetMELoadings()
SetMELoadings
GetMELoadings()
GetMELoadings
SetEnrichrTable()
SetEnrichrTable
GetEnrichrTable()
GetEnrichrTable
SetModuleScores()
SetModuleScores
GetModuleScores()
GetModuleScores
GetTOM()
GetTOM
SetModuleUMAP()
SetModuleUMAP
GetModuleUMAP()
GetModuleUMAP
SetModuleTraitCorrelation()
SetModuleTraitCorrelation
GetModuleTraitCorrelation()
GetModuleTraitCorrelation
SetModulePreservation()
SetModulePreservation
GetModulePreservation()
GetModulePreservation
SetMotifs()
SetMotifs
GetMotifs()
GetMotifs
SetMotifMatrix()
SetMotifMatrix
GetMotifMatrix()
GetMotifMatrix
SetPFMList()
SetPFMList
GetPFMList()
GetPFMList
SetMotifTargets()
SetMotifTargets
GetMotifTargets()
GetMotifTargets
SetMotifOverlap()
SetMotifOverlap
GetMotifOverlap()
GetMotifOverlap
SetMotifScores()
SetMotifScores
GetMotifScores()
GetMotifScores
SetDegrees()
SetDegrees
GetDegrees()
GetDegrees
GetTFRegulons()
GetTFRegulons
SetTFRegulons()
SetTFRegulons
GetTFEval()
GetTFEval
SetTFEval()
SetTFEval
GetRegulonScores()
GetRegulonScores
SetRegulonScores()
SetRegulonScores
GetEnrichrRegulonTable()
GetEnrichrRegulonTable
SetEnrichrRegulonTable()
SetEnrichRegulonTable
GetMetacellParams()
GetMetacellParams
SetMetacellParams()
SetMetacellParams
SetTFNetwork()
SetTFNetwork
GetTFNetwork()
GetTFNetwork

Seurat wrappers

Wrapper functions to run Seurat commands on the metacell data

NormalizeMetacells()
NormalizeMetacells
ScaleMetacells()
ScaleMetacells
RunPCAMetacells()
RunPCAMetacells
RunHarmonyMetacells()
RunHarmonyMetacells
RunUMAPMetacells()
RunUMAPMetacells
DimPlotMetacells()
DimPlotMetacells

Customization

Customization functions

ResetModuleColors()
ResetModuleColors
ResetModuleNames()
ResetModuleNames

Other

Other functions

ConstructPseudobulk()
ConstructPseudobulk
ReassignModules()
ReassignModules
GetActiveWGCNAName()
GetActiveWGCNAName